Unfortunately, the percentage of do-it-yourselfers in some quarters is at least 22%. Taking more estrogen than needed does not do anything to grow breasts but it will make you more vulnerable to blood clots which can kill you. You can get into big trouble without a physician monitoring your blood levels and adjusting the drugs and the dosages for your body. You want just the right drugs and dosages to get the right levels. All bodies are different, they start out with different blood levels of hormones and achieve different levels from HT. You cannot do that yourself and it is dangerous to try. The theory behind trans woman HT is to maintain blood levels of estrogen in the range of the average female and reduce the levels of testosterone. IF YOU ARE FOLLOWING A DIY HT PATH, YOU ARE RISKING YOUR HEALTH In HT for trans women, this mechanism is turned off by estradiol. For natal males, this mechanism works by creating a substance called gonadotropin releasing factor that trickles down into the pituitary beneath it and triggers the release of a couple of hormones that stimulate the testes to manufacture and release testosterone.
Taking estradiol sends a message to the hypothalamus that all is well with sex hormone levels in the body and that it need not stimulate testosterone production and release. Estradiol stimulates the estrogen receptors in the breasts directly but it also has an effect on the brain.
The way this is usually done is through HT. In order to get breast growth, one has to stimulate the estrogen receptors and not stimulate the testosterone receptors. These sex hormone receptors are in opposition to one another. To begin with, on the cells of the breast there are receptors for sex hormones, estrogen and testosterone. We know how hormone therapy (HT) grows breasts in trans women. I now have the benefit of more research and first-hand experience with breast augmentation. There have been some big changes about getting hormone therapy (HT) for breast development from providers. A few more pieces of the basic biology are now available. I have been asked to update my previous post about breast development.
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